Heart/cardiovascular disease state
samples available
Please contact us to find out how we can provide you with the heart or vascular tissues you require.
Via our partner clinical biobanks, post mortem donor center and
organ transplant network we can provide a wide range of
diseased-heart tissue samples, as well as diagnostic remnants, which
are chiefly whole blood, serum and/or plasma.
We can provide, from biorepositories or prospective tissue
collections, whether as tissues or diagnostic blood remnants,
depending on whether the disease is surgically resected and the
data and format you require:
- aortic valve
- stenosis
- arteriosclerosis
- atherosclerosis
- cardiac atrophy
- heart bypass operations
- coronary/other calcification
- cardiomyopathy (ischemic and non-ischemic cardiomyopathy, dilated cardiomyopathy)
- congestion
- epicarditis
- coronary fibrosis
- heart failure
- ventricular assist device placement
- hypertension
- hypertrophy
- cardiac infarction
- cardiac inflammation
- mitral valve (Myxomatous degeneration, myxoid degeneration, fibrosis, cardiac valvulopathy, severe mitral regurgitation, Nodular myxomatous degeneration of cardiac valve)
- myocyte nucleomegaly
- myxoid degeneration
- cardionecrosis
- pacemaker placement
- papillary fibroelastoma (rare)
- heart transplant rejection (rare)
- sarcoidosis of the heart (rare)
- stent placement
- heart wall thickening
Please note that these conditions are most widely available as diagnostic remnant blood samples only, but some may be available as archival FFPE, or post mortem.
Donor types
Clinical tissue donors
Certain tissues are available from our clinical tissue donor partner
sites. Clinical donors range in age from their 20s (very rare) to 80s.
sites. Clinical donors range in age from their 20s (very rare) to 80s.
Clinical tissue sample formats:
Samples are often available with FFPE, frozen tissue, plasma, serum
and buffy coat sometimes available from the same donor, with
pathology details also available. Medical history & follow-up data may
also be available.
and buffy coat sometimes available from the same donor, with
pathology details also available. Medical history & follow-up data may
also be available.
Post mortem tissue donors
Accio Biobank Online is delighted to announce that to further expand the range of fresh organ and tissue research we can support, we have partnered with a highly experienced organ procurement network. This means that we can facilitate your access to non-transplantable organs and tissues kindly donated by organ donors.
Post mortem donors recovered from our partner body donation
center are mostly aged 60+. The shortest interval between death and
sampling is usually 12 hours, so the more flexible you can be, the
faster we can collect for you. or more hours will greatly increase the
number of donors available to study.
center are mostly aged 60+. The shortest interval between death and
sampling is usually 12 hours, so the more flexible you can be, the
faster we can collect for you. or more hours will greatly increase the
number of donors available to study.
Organ transplant donor hearts can usually be recovered within 1 hour of aortic cross clamp, and shipped fresh on transplant buffer via next flight out courier.
Post mortem organ/ tissue sample formats:
Whole hearts, cardiac tissue samples and vascular tissue samples
are available fresh, frozen or fixed in 10% NBF. A pathology report is
not available, although a donor/next of kin medico-social
questionnaire is available and infectious disease testing is also
available via this route.
are available fresh, frozen or fixed in 10% NBF. A pathology report is
not available, although a donor/next of kin medico-social
questionnaire is available and infectious disease testing is also
available via this route.
Organ/ tissue sample types and sizes:
Working with our partner post mortem donor facilities, we can provide:
- whole hearts
- arteries from any location, including the carotid artery, aorta, pulmonary artery
- veins from any location, including carotid vein, pulmonary vein etc
- any surrounding tissues
- a range of heart diseases, such as those listed above
- normal hearts
